As he celebrates his birthday on May 6, take a look at images of George Clooney throughout his career.
In 2002, Clooney stepped behind the camera for his directorial debut, taking on "Confessions of a Dangerous Mind" with Drew Barrymore and Sam Rockwell.
Matt Cowan/Getty Images
Alex Wong/Getty Images
Matt Porteous/Kensington Palace via CNN
Chris Jackson/Getty Images
Russian Federal Space Agency
Thierry Chesnot/Getty Images
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