As he celebrates his birthday on May 6, take a look at images of George Clooney throughout his career.
In 2002, Clooney stepped behind the camera for his directorial debut, taking on "Confessions of a Dangerous Mind" with Drew Barrymore and Sam Rockwell.
Adele.com via CNN
Thierry Chesnot/Getty Images
iStock / Terraxplorer
Stephen Maturen/Getty Images
Irving Police Department via CNN
iStock / Bosca78
Kevin Winter/Getty Images
Kena Betancur/Getty Images
Scott Olson/Getty Images
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