As he celebrates his birthday on May 6, take a look at images of George Clooney throughout his career.
"O Brother, Where Art Thou?," the Coen Brothers' 2000 take on Homer's "Odyssey," gave Clooney the chance to have the best-reviewed performance of his career to that point.
Thierry Chesnot/Getty Images
Robert Evans/Handout via Getty Images
Win McNamee/Getty Images
Drew Angerer/Getty Images
Frazer Harrison/Getty Images
iStock / damircudic
National Park Service
Jason Merritt/Getty Images
Andrew Redington/Getty Images
Karen Ducey/Getty Images
Theo Wargo/Getty Images
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