Renee Zellweger through the years

Published On: Jan 20 2012 02:45:07 PM CST   Updated On: Apr 25 2014 09:24:12 AM CDT

Oscar-winner Renee Zellweger, who celebrates her 45th birthday on April 25, has become one of Hollywood's mainstays over the years. Let's take a look back at her career so far.

Zellweger through years - Nurse Betty
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USA Films

Zellweger as delusional nurse Betty Sizemore, standing with a cutout of Greg Kinnear's character, in 2000's "Nurse Betty."

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