Bush carried the ball six times and netted 1 yard, but he made his mark as a pass-catcher. He turned a short pass from Matthew Stafford into a 67-yard gain on the Lions' first offensive series, leading to a field goal.
Like Bush, Stafford played only the first half. The Lions quarterback completed 12 of 25 passes for 166 yards and a 9-yard touchdown to Tony Scheffler.
Patriots quarterback Tom Brady also played the first two quarters. He went 16-for-24 for 185 yards with one interception.
New England wide receiver Kenbrell Thompkins, an undrafted rookie out of Cincinnati, made eight receptions for 116 yards.
The Patriots (2-1) committed three turnovers, while the Lions (2-1) never gave the ball away.
Panthers 34, Ravens 27
Carolina scored three defensive touchdowns en route to a win at M&T Bank Stadium in Baltimore.
Drayton Florence picked off a Joe Flacco pass in the second quarter and took it back 71 yards for a score.
Two plays later, Luke Kuechly forced a fumble from Raves running back Bernard Pierce. Thomas Davis picked up the loose ball and ran 2 yards for a touchdown that put the Panthers on top 21-7.
In the third quarter, D.J. Moore intercepted a pass thrown by Tyrod Taylor and raced for a 33-yard touchdown.
Flacco finished 18-for-24 for 169 yards with one touchdown and two interceptions. Running back Ray Rice had 16 carries for 62 yards, both game highs, and he scored a 1-yard touchdown that gave Baltimore (2-1) the game's first points.
Panthers quarterback Cam Newton went 10-for-19 for 99 yards, and he added 20 yards on two carries. Running back Tauren Poole gained 36 yards on 15 carries for Carolina (2-1).