MINNEAPOLIS (AP) -

Denard Span had a game-ending RBI double in the 10th inning and the Minnesota Twins rallied for a 4-3 victory over the Kansas City Royals on Thursday night.

Trailing 3-1, the Twins capitalized on a bases-loaded walk by Royals closer Greg Holland in the eighth and Trevor Plouffe's homer in the ninth to tie it.

Alexi Casilla led off 10th with a double to right-center off Francisley Bueno (1-1) that fell just beyond the glove of diving center fielder Lorenzo Cain, who injured his leg on the play and had to leave the game. Span then hit a double over the head of right fielder Eric Hosmer for the win.

Closer Glen Perkins (3-1) pitched two scoreless innings for the win.

Josh Willingham also connected for Minnesota and Salvador Perez had two RBIs for the Royals.