Pettersen said Wie should be given some space to find her game at her own pace.
"I think you should give her a break," Pettersen said. "She just graduated, four years in college. That's pretty impressive to do that on the sideline of trying to compete out here. So now it's obviously a little different world for her. Now it's all about golf, and she has to kind of find her schedule, how to kind of work it out the best way for her."
Pettersen, meanwhile, believes her own game is in good shape.
"My game is very solid," Pettersen said. "My ball striking is good. My short game is good. And my putting has been really good so far."
Her day got off to a hectic start when she overslept and had to rush to make her tee time, skipping breakfast.
"For me breakfast is kind of my most important meal," Pettersen said. "I didn't really have time. I thought it was more important to get stretched and loosened up. Even though it's hot. It's fine. Sometimes that's a good thing. You don't have time to think about stuff."
The intense heat and humidity players and fans dealt with in Thursday's first round eased only slightly on Friday. The final two days of the tournament are expected to be more pleasant.
"Hopefully we're done with the two hot days, and they're all calling for a cooler weekend," Pettersen said. "Which I'm all for. It's been two really hot days."