2000 - Wins the Tour de France for a second consecutive year.
2000 - Publishes book "It's Not About the Bike: My Journey Back to Life."
2001 - Wins the Tour de France for the third time.
2002 - Wins his fourth consecutive Tour de France.
2002 - A 21-month investigation into whether the U.S. Postal Team used performance enhancing drugs during the 2000 Tour de France closes after finding no evidence of illegal drug use.
July 27, 2003 - Armstrong wins his fifth consecutive Tour de France by 61 seconds.
June 15, 2004 - Announces he is suing the author of a book accusing him of taking performance-enhancing drugs.
June 21, 2004 - A Paris court throws out a request by Armstrong for an emergency ruling ordering the publishers of a book detailing suggestions of doping to insert a denial by Armstrong.
July 25, 2004 - Wins his sixth consecutive Tour de France.
April 18, 2005 - Announces that he will retire after competing in the 2005 Tour de France.
July 24, 2005 - Wins his seventh Tour de France.
Dec. 14, 2005 - Armstrong is indicted in an Italian court and is ordered to stand trial for defaming cyclist Filippo Simeoni. Charges are later dropped in April 2006.
May 31, 2006 - A report from the International Cycling Union is released that clears Armstrong's name of doping allegations from 1999.
Sept. 9, 2008 - Announces his return to professional cycling.
March 24, 2009 - Falls along with 15-20 other riders during a race in Spain and breaks his collarbone.
July 26, 2009 - Armstrong comes in third place in the Tour de France.
May 20, 2010 - He crashes during the Amgen Tour of California and is taken to a hospital. The same day he denies allegations of doping made by former teammate Floyd Landis
July 21, 2010 - Armstrong hires a defense lawyer to represent him in a federal investigation into allegations of fraud and doping.
July 25, 2010 - Armstrong comes in 23rd place in his final Tour de France.
Feb. 16, 2011 - Armstrong announces his retirement from the world of professional cycling, saying he wants to devote more time to his family and the fight against cancer.
Feb. 3, 2012 - Justice Department prosecutors announce they are closing a criminal probe of Armstrong without filing charges he used performance enhancing drugs.
June 12, 2012 - The U.S. Anti-Doping Agency (USADA) notifies Armstrong of an investigation into new doping charges. In response, Armstrong says that the USADA intends to "dredge up discredited" doping allegations against him in a bid to strip him of his seven Tour de France victories.
June 29, 2012 - The USADA announces that it has filed doping charges against Armstrong. Armstrong's attorney calls the decision to charge "wrong" and "baseless."
July 9, 2012 - Armstrong files a federal lawsuit in a Texas district court to halt the doping case against him. The suit asks the court to file an injunction against the USADA by July 14th-a deadline the USADA stipulated for Armstrong to agree to contest the charges or accept sanctions. Hours later, U.S. District Judge Sam Sparks dismisses Armstrong's lawsuit. In a sharply-worded ruling, the judge states Armstrong's 80-page complaint is full of legally irrelevant claims. The judge urges Armstrong to re-file without "any improper argument, rhetoric, or irrelevant material."
July 10, 2012 - Armstrong re-files the lawsuit. The complaint is substantially shorter than the original and Armstrong again asks the court to file an injunction against the USADA by July 14.