The FDA approves the first of a new type of anti-HIV drug called Fuzeon (also known as enfuvirtide or T-20). This drug is designed to prevent the entry of HIV into human cells.
The HBO TV miniseries "Angels in America" premieres, starring Al Pacino and Meryl Streep. Adapting a Pulitzer Prize-winning play of the same name, it follows two couples as they struggle to stay together during the AIDS epidemic in the 1980s. It wins multiple Emmy and SAG awards.
George W. Bush launches PEPFAR, the U.S. President's Emergency Plan to combat AIDS worldwide. "This historic commitment is the largest by any nation to combat a single disease internationally," according to the PEPFAR website.
For the first time, the FDA approves a generic AIDS drug made by a foreign country, allowing PEPFAR to provide cheaper medications overseas. The patent on AZT also reaches an end, allowing more generic versions of the drug.
Singer Bono launches Product Red. Profits from the line of consumer goods are designated to fight the AIDS epidemic worldwide. "I feel a bit of a fraud, a bit of a loser because we are not winning in the war against AIDS," Bono says.
Bill Gates announces that he will step down as the head of Microsoft in order to donate his time to the Gates Foundation, the largest private source of funding in the fight against HIV/AIDS.
Atripla, the first effective one-a-day pill to treat HIV, is approved in the U.S.
President Obama removes a travel ban preventing HIV-positive people from entering the U.S. This leads to the announcement that the International AIDS Conference will be held in the U.S. for the first time in more than 20 years.
Washington's health department reports that D.C. has a higher rate of HIV and AIDS prevalence than West Africa, at 3%.
The trial of a microbicide gel, CAPRISA 004, shows that it reduces the risk of a woman becoming infected with HIV during sex by almost 40%.
A third phase of a PrEP trial reveals that drugs used to treat HIV may also be effective in preventing infection. Subjects taking a once-daily antiretroviral pill were 44% less likely to be HIV-positive after male-to-male sex.
The National Institutes of Health publishes the results of a study that says taking antiretroviral drugs at the onset of HIV leads to a dramatic reduction in HIV transmission to an uninfected heterosexual partner.
"These results represent another significant step forward in HIV prevention and reinforce the importance of people everywhere knowing their HIV status and being linked to services for HIV prevention, care and treatment," CDC Director Thomas R. Frieden says.
The 19th International AIDS Conference takes place in Washington, bringing together more than 25,000 doctors, scientists, AIDS activists, politicians, philanthropists, drug company representatives, people living with HIV and heads of state from around the world. One of the main themes is the launch of "Towards an HIV Cure."
UNAIDS announces that new HIV infections have dropped more than 50% in 25 low- and middle-income countries, and the number of people getting antiretroviral treatment has increased 63% in the past two years. More than 34 million people are still living with HIV, according to global estimates.
Researchers announce they have "functionally cured" a Mississippi toddler of HIV. They believe that early intervention -- in this case within 30 hours of birth -- with three antiviral drugs was key to the outcome.