Take a look back at some of the more memorable casting changes in the history of television.
After Duchovny's semi-departure, the show introduced two new central characters, FBI agents John Doggett (Robert Patrick) and Monica Reyes (Annabeth Gish), to join Gillian Anderson's Dana Scully.
Lucy Richardson/ Reuters
iStock / gbh007
National Portrait Gallery, London
iStock / mashabuba
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