"Iron Man 3" took off with the second-biggest U.S. opening weekend ever, pulling in an estimated $175.3 million in ticket sales. Check out the 20 movies that have made the biggest splashes on their opening weekends, according to Box Office Mojo.
8. "The Twilight Saga: New Moon." Release date: 2009. Domestic gross on opening weekend: $142.8 million.
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