"Iron Man 3" took off with the second-biggest U.S. opening weekend ever, pulling in an estimated $175.3 million in ticket sales. Check out the 20 movies that have made the biggest splashes on their opening weekends, according to Box Office Mojo.
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11. "Pirates of the Caribbean: Dead Man's Chest." Release date: 2006. Domestic gross on opening weekend: $135.6 million.